Southern States Colorectal Cancer Study
A multi-institutional research effort to understand colorectal cancer in African Americans through deep molecular profiling.
About Colorectal Cancer
Colorectal cancer (CRC) is the second leading cause of cancer-related mortality in both the United States and globally. Substantial evidence indicates that CRC may occur due to complex interactions between socio-environmental, lifestyle, clinical and genetic factors.
Earlier studies have provided important insights into disease risk, but they offer limited resolution into the molecular mechanisms through which genetic susceptibility and environmental exposures interact to drive disease development and influence prognosis.
This study focuses on African American/Black individuals because even though they experience disproportionate burden of CRC morbidity and mortality, they remain underrepresented in multi-omics research. By integrating multi-omics data with detailed socio-environmental information, we aim to close this gap.
Watch Our Story
Learn more about the SSCRCS study and why it matters
Study Phases
Protocol Design and IRB Approval
Finalize study design and obtain IRB protocol approval.
Recruitment and Biospecimen Collection
Identify eligible participants, conduct survey and collect blood samples.
Multi-omics Assay
Generate genomic, transcriptomic, epigenomic, proteomic and metabolomic data.
Risk Model Development & Publication
Integrating molecular data with epidemiologic predictors to develop CRC risk models and publish findings in peer-reviewed journals.